projects

Research projects I'm currently working on.

research
  1. Generative Antibody Design with Protein Language Models
    Marco De Negri, Giovanni Guidarini, Andreas Krause, and Scott Sussex
    Learning & Adaptive Systems Group, ETH Zürich, Spring 2026 – present
    Fine-tuning ESM2 with Direct Preference Optimization to generate higher-affinity antibody variants.
    Website
  2. Training and Visualising Degeneration Apertus Probes
    Lorenzo Baggi, Marco De Negri, Moritz Reihs, Luca Sartori, Eduard Durech, Anna Hedström, and Valentina Pyatkin
    ETH AI Center, Apertus Group, Spring 2026 – present
    Token-level probes to detect and steer generation degeneration in a LoRA-adapted LLM.
    Website
  3. Goal-driven 3D Map Generation with Reinforcement Learning
    Lorenzo Baggi, Marco De Negri, Vassili De Palma, Alessio Salvatore, Daniel Barath, and Jelena Trisovic
    Computer Vision and Geometry Lab, ETH Zürich, Spring 2026
    An RL agent that dynamically allocates resolution in a 3D map under a tight memory budget.
    Website